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Life sciences · Preprint
arXiv · October 29, 2026
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Integrated sensing and communications (ISAC) systems using 5G and beyond signals of opportunity enable joint wireless sensing and communication using shared infrastructure and spectrum resources. While multistatic ISAC can increase sensing coverage with spatially distributed receivers, dense and dynamic clutter can significantly degrade bistatic range and Doppler estimation, leading to errors in target localization and velocity estimation. This paper presents a multistatic ISAC framework with clutter suppression for high-fidelity estimation of target position and velocity. Distributed clutter is modeled with randomly located scatterers with varying Doppler spreads and radar cross sections to capture dense and dynamic clutter effects. A broad range of conventional signal processing baselines are evaluated for clutter suppression, showing limited robustness under strong clutter conditions. To address this limitation, deep learning-based clutter suppression methods are introduced to improve robustness against dense and dynamic clutter by employing residual and attention-enhanced deep neural network architectures that directly enhance target responses from clutter-contaminated observations. These methods substantially outperform conventional approaches in target position and velocity estimation across diverse clutter conditions in multistatic ISAC.