Life sciences · Preprint
arXiv · September 24, 2026
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Deploying real-time speech enhancement on resource-constrained devices requires meeting strict latency, memory, and energy constraints. Microcontroller NPUs can accelerate neural inference under these constraints, but only through a restricted set of operators in static, integer-quantized graphs. Recent speech-enhancement networks have reduced parameter counts and MACs to levels nominally suitable for microcontrollers, but their operators and execution patterns often remain incompatible with restricted NPUs. We address this gap by redesigning LiSenNet, a 37k parameter sub-band dual-path model, for the STM32N6570-DK Neural-ART accelerator. We replace its recurrent bottleneck with convolutional frequency and temporal mixers, reformulate unsupported operations as static int8-compatible primitives, and use bounded decoder activations to preserve quality after quantization. On VoiceBank-DEMAND, the final NPU-compatible model matches or exceeds the recurrent LiSenNet baseline, reaching PESQ 3.08 versus 3.01 in FP32 and 3.01 versus 2.93 in int8. Deployed on a microcontroller, it processes each 16 ms input hop in 4.83 ms, corresponding to a real-time factor of 0.30. Stateless receptive-field recomputation is an order of magnitude slower at the same frame rate despite higher accelerator utilization. These results show that parameter count and operator compatibility, quantization range, and persistent streaming state must be co-designed to achieve efficient real-time speech enhancement on restricted NPUs.