Life sciences · Preprint
arXiv · September 4, 2026
Raises a question worth testing. It does not answer one.
This is a theoretical mathematics paper deriving approximation rates for shallow neural networks with general activation functions in mixed Sobolev spaces. The work establishes a Fourier-block principle and identifies optimal algebraic approximation exponents for specific activations (ReLU^k, B-splines, ELU, cosine), but does not report empirical validation or application to clinical or biological systems.
Preprint.
Global approximation rate has algebraic order min{α,ρ} for target functions of mixed smoothness α, where ρ is univariate approximation order For ReLU^k, optimal algebraic approximation exponent is min{α,k+1} up to logarithmic factors Exponent min{α,k+1} achieved for cardinal B-splines and soft-ReLU^k
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The source did not state who this applies to in practice.
This is a theoretical mathematical analysis establishing approximation bounds for neural networks; it addresses a mechanistic question about activation function properties rather than empirical clinical or biological evidence.
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We investigate the best $L_2$ approximation of mixed Sobolev spaces by shallow neural networks with $n$ neurons and general activation functions. We first establish an activation-independent Fourier-block principle: if an activation has univariate approximation order $ρ$ in the sense of the Fourier-block property, then the global approximation rate has algebraic order $\min\{α,ρ\}$ for target functions of mixed smoothness $α$, up to explicit logarithmic factors. To verify this property for concrete activations, we introduce a structured univariate approximation condition that implies the Fourier-block property with explicit parameters. For $\mathrm{ReLU}^k$, a matching algebraic lower bound identifies $\min\{α,k+1\}$ as the optimal algebraic approximation exponent in any dimension, up to logarithmic factors in the upper bound. The framework also yields the exponent $\min\{α,k+1\}$ for cardinal B-splines and soft-$\mathrm{ReLU}^k$, and the full mixed-smoothness exponent $α$ for ELU and cosine activations, again up to logarithmic~factors.
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