Obesity / Overweight / Overnutrition · Observational Study

The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for Obesity

ClinicalTrials.gov · September 8, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a completed observational registry record describing a phenotyping study of eating behavior and food preferences in Pima Indians and Caucasians, designed to identify environmental risk factors for obesity. No study results are posted in this registry entry, so no evidence on associations or outcomes can be evaluated.

What was studied

Observational. Obesity, Overweight, Overnutrition; age from 18 Years; to 65 Years. Intervention: non-diabetic volunteers. n = 669. 1 site: United States.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is a completed observational study registration with no reported results, designed to characterize eating behavior and food preference phenotypes as obesity risk factors in a specific population.

Study design

As stated by the source record.

MethodsEcologic Or Community model. Cross Sectional time perspective. Primary outcome measure: Ad libitum food intake (assessed at Baseline, up to day 3)

DesignObservational

PopulationObesity, Overweight, Overnutrition; age from 18 Years; to 65 Years

Sample size669

Interventionnon-diabetic volunteers

Setting1 site: United States

Reported figures

Quoted from the source exactly as published.

Planned enrollment669

Primary outcome measureAd libitum food intake

Assessment timeframeBaseline, up to day 3

Caveats

Results are not posted in this registry record; no outcomes, effect sizes, or associations can be determined from this source.
Study design, methods, analytical approach, and participant retention are not described in the registry entry.
No information on whether the study has been published or results made available elsewhere.
Observational design permits phenotyping but cannot establish causality.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

moderate

Observational design with structured phenotyping; no intervention or randomization.

Directness

moderate

Direct measurement of eating behavior and food preferences as putative risk factors for obesity.

Consistency

insufficient

No results reported in registry; consistency cannot be assessed.

Risk of bias

insufficient

Registry record does not describe methods, blinding, or analytical approach.

Sample adequacy

moderate

Enrollment of 669 participants is reasonable; composition and retention not described.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT00342732). This is a study registration, not published results. Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 669 participants (ACTUAL). Conditions: Obesity, Overweight, Overnutrition. Primary outcome measures: Ad libitum food intake , Baseline, up to day 3. Brief summary: The prevalence of obesity in the United States has reached alarming proportions with 33% of adults over the age of 20 being overweight. Obesity is more than twice as prevalent, however, in the Pima Indians of Arizona. Although there have been a number of advances in our understanding of the genetics of obesity, the environmental influences on the genetic expression of obesity requires further investigation. In an effort to understand some of the influences on the high prevalence of obesity in the Pima Indians, the present study was designed to investigate eating behaviors and food preferences, most especially the preference for high fat foods, in sib-pairs of Pima Indians who have been previously genotyped in our genomic scan for loci linked to diabetes/obesity. Most specifically, we will utilize several questionnaires and methods of assessing eating behavior and the preference for high fat foods to create a food intake phenotype. In addition, we will study Caucasians so that comparisons can be made between these two groups. We will make these evaluations by assessing eating behavior, food preferences including usual fat intake and preferences for high fat foods, body image perceptions, and energy expenditure. It is hoped that the data gathered from this study will elucidate some of the risk factors for the development of obesity among the Pima Indians.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

ObesityOverweightOvernutritionNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT00342732