Life sciences · Preprint
arXiv · October 8, 2026
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Generalist graph anomaly detection (GAD) aims to build a foundation model that detects anomalies on arbitrary unseen graphs without retraining or fine-tuning. Sufficient data are essential for foundation model training, yet generalist GAD still faces a data shortage, as real-world anomalous graphs are scarce and costly to collect and annotate. To fill this gap, we propose AG-FORGE, an Anomalous Graph generation Forge for automatic synthesis of anomalous graphs, exploring the feasibility of synthetic data-driven training for generalist GAD. Empirically, we find that synthetic data can achieve performance comparable to real-world training, but fail to push the performance boundary further due to the limited capacity of existing methods. To further unlock model capacity as training data scale up, we develop TS-GGAD, a Topology-Semantic coordinated Generalist GAD that captures complementary topological and semantic anomaly evidence, together with a curriculum learning strategy tailored to large-scale synthetic training. Extensive experiments on 14 real-world datasets demonstrate that TS-GGAD, trained on data generated by AG-FORGE, significantly outperforms state-of-the-art methods.