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Life sciences · Observational Study
ClinicalTrials.gov · November 6, 2026
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Observational Study.
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Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
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Registry record from ClinicalTrials.gov (NCT07920913). This is a study registration, not published results. Lead sponsor: Sergio Gabriel Susmallian. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 56716 participants (ACTUAL). Conditions: Fibromyalgia (FM), Depression. Primary outcome measures: Proportion of Fibromyalgia Patients With Documented Psychiatric Comorbidity , January 1, 2018, to December 31, 2025. Brief summary: Fibromyalgia is a chronic condition characterized by widespread pain, fatigue, sleep disturbances, and difficulties with daily activities. Many people with fibromyalgia also experience psychiatric disorders, particularly depression and anxiety. However, the relationship between these conditions and long-term disability remains incompletely understood. This nationwide study examines the relationship between fibromyalgia, psychiatric disorders, and disability among individuals whose claims were evaluated by the Israeli National Insurance system between 2018 and 2025. The study compares two groups: individuals assessed through the general disability system and those assessed through the occupational injury system. It investigates differences between women and men, psychiatric comorbidity, assigned disability severity, temporary and permanent disability, and changes over time. The research uses existing anonymized administrative records. No experimental treatment, additional examinations, or direct patient participation is required. The findings may help improve understanding of psychiatric comorbidity in fibromyalgia and support more comprehensive clinical and occupational disability assessments.