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Life sciences · Interventional Study
ClinicalTrials.gov · November 9, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07915440). This is a study registration, not published results. Lead sponsor: Hospital Clinico Universitario San Cecilio. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 118 participants (ESTIMATED). Conditions: Chronic Pain. Interventions: BEHAVIORAL: Meaning Based Group Psychotherapy; BEHAVIORAL: Cognitive Behavioural Psychotherapy. Primary outcome measures: Beck Depression Inventory , Changes will be assessed from pre-treatment to immediately after the intervention, and also at 3-month follow-up; Meaning in Life Questionnaire (MLQ) , Changes will be assessed from pre-treatment to immediately after the intervention, and also at 3-month follow-up; The Multidimensional Existential Meaning Scale (MEMS) , Changes will be assessed from pre-treatment to immediately after the intervention, and also at 6-month follow up; Purpose In Life (PIL) , [Time Frame: Changes will be assessed from pre-treatment to immediately after the intervention, and also at 3-month follow up; Pain Catastrophizing Scale , Changes will be assessed from pre-treatment to immediately after the intervention, and also at 3-month follow up. Brief summary: The aimes of this study is to determine whether Meaning-Based Psychotherapy (MBP) is an effective therapy for improving sense of purpose, reducing depression, and improving quality of life in people with chronic pain and to verify the effectiveness of the MBP intervention for participants in a randomized controlled trial (RCT) by comparing it with the optimized usual care (Cognitive-behavioural Psychotherapy por chronic pain).