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Infections and Bacterial Resistance / Nosocomial Infections in ICU · Journal article
International Journal for Multidisciplinary Research · July 27, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a single-centre descriptive antibiogram documenting in vitro antibiotic susceptibility of bacterial isolates from ICU patients at a tertiary hospital in Bengaluru over 6 months. It reports susceptibility percentages for 14 organisms but does not measure clinical efficacy, patient outcomes, or impact of empirical therapy guided by these patterns. The findings are locally useful for institutional empirical prescribing guidance and antimicrobial stewardship but do not constitute evidence of clinical benefit.
Single-centre prospective observational study; antibiogram survey. 102 eligible ICU patients admitted with infectious diseases at ESIC MC-PGIMSR and Model Hospital, Rajajinagar, Bengaluru, India, after institutional ethics committee approval and informed consent.. Intervention: Susceptibility testing of bacterial isolates using standardised microbiological methods (CLSI standards). n = 102. Single centre: ESIC MC-PGIMSR and Model Hospital, Rajajinagar, Bengaluru, India.
Enterococcus faecalis showed 100% susceptibility to Penicillin, Linezolid, Tigecycline, Vancomycin, and Teicoplanin Staphylococcus aureus exhibited 16.7% susceptibility to Penicillin but remained fully susceptible to Linezolid, Levofloxacin, and Teicoplanin Klebsiella aerogenes showed pan-resistant profile among Gram-negative isolates
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
This antibiogram provides local institutional data to inform empirical antibiotic selection in this ICU and supports antimicrobial stewardship efforts. However, the absence of clinical outcome data means it should be used as guidance for prescribing patterns rather than as evidence that any particular empirical regimen improves patient outcomes.
Single-centre descriptive antibiogram from a 6-month observational study with 102 patients; no comparator, no hypothesis test, and no clinical outcome data—useful for local empirical guidance but not evidence of efficacy or clinical impact.
As stated by the source record.
Quoted from the source exactly as published.
This antibiogram provides local institutional data to inform empirical antibiotic selection in this ICU and supports antimicrobial stewardship efforts. However, the absence of clinical outcome data means it should be used as guidance for prescribing patterns rather than as evidence that any particular empirical regimen improves patient outcomes.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Background: Antimicrobial resistance is an increasing problem in intensive care settings where empirical antibiotic selection is often needed before culture data are available. Institution-specific antibiograms are useful for clinicians to identify suitable empirical therapy and promote antimicrobial stewardship activities. Objective: The objective of this study was to describe the in vitro antibiotic susceptibility patterns of bacterial isolates from patients admitted to the intensive care unit with infectious diseases at a tertiary care hospital in Bengaluru as part of a larger prospective observational study correlating the neutrophil to lymphocyte ratio with antibiotic efficacy and clinical outcomes. Methods: This antibiogram analysis was a part of a six-month prospective observational study conducted in the intensive care unit of ESIC MC-PGIMSR and Model Hospital, Rajajinagar, Bengaluru, involving 102 eligible patients recruited after institutional ethics committee approval and informed consent. Bacterial isolates collected from clinical specimens were identified by standard microbiological procedures, and antibiotic susceptibility testing was performed according to Clinical and Laboratory Standards Institute standards. Susceptibility was represented as the percentage of susceptibility for each organism-antibiotic combination. Results: Three Gram positive and eleven Gram negative organisms were tested. Enterococcus faecalis remained entirely sensitive to Penicillin, Linezolid, Tigecycline, Vancomycin and Teicoplanin while Staphylococcus aureus exhibited considerable resistance to Penicillin (16.7 percent susceptible) but remained fully susceptible to Linezolid, Levofloxacin and Teicoplanin. Klebsiella aerogenes showed a pan-resistant profile among Gram-negative isolates, whereas Pseudomonas aeruginosa remained vulnerable to most anti-pseudomonal drugs. Elizabethkingia meningoseptica was sensitive to only Cotrimoxazole and Cefoperazone-Sulbactam. Conclusion: Significant resistance was reported to several routinely used antibiotics among the ICU isolates in this institution. These findings underscore the necessity of local antibiogram surveillance and formalized antimicrobial stewardship to guide empirical prescribing and sustain the utility of last-resort medicines.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.