Life sciences · Phase 2/3 Trial
ClinicalTrials.gov · October 23, 2026
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Phase 2/3 Trial.
No findings were extractable from the material analysed.
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Registry record from ClinicalTrials.gov (NCT07149649). This is a study registration, not published results. Lead sponsor: Swiss Cancer Institute. Recruitment status: RECRUITING. Phase: PHASE2, PHASE3. Study type: INTERVENTIONAL. Enrollment: 230 participants (ESTIMATED). Conditions: Metastatic NSCLC - Non-Small Cell Lung Cancer. Interventions: DRUG: Magnesiocard; DRUG: Magnesium Diasporal; OTHER: Microcrystalline cellulose; OTHER: Isotonic saline solution 0.9%. Primary outcome measures: Primary endpoint of Phase II part: Progression-free survival (PFS) , From randomization to PD or death, up to 10 years; Primary endpoint of Phase III part: Overall survival (OS) , From randomization to PD or death, up to 10 years. Brief summary: This study investigates whether adding magnesium to the standard chemo-immunotherapy for advanced non-small cell lung cancer (NSCLC) can improve treatment outcomes. Magnesium is important for immune function, and low levels during chemotherapy are common. Participants are randomly assigned to receive either magnesium or a placebo, both as infusions and tablets. Neither the participants nor the doctors know who receives which treatment. The study compares the two groups to see if magnesium helps and how well it is tolerated.