Life sciences · Interventional Study
ClinicalTrials.gov · November 9, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07073781). This is a study registration, not published results. Lead sponsor: Leeds Beckett University. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 70 participants (ESTIMATED). Conditions: Impaired Glucose Tolerance (Prediabetes), Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Overweight (BMI > 25), Cognitive Dysfunction, Neurovascular Coupling Mechanism and Cognitive Function, Obese Adults. Interventions: DIETARY_SUPPLEMENT: Lab4p Probiotic Consortium; OTHER: Placebo. Primary outcome measures: Verbal Memory Performance , Baseline to Week 12 (end of treatment).. Brief summary: This 12-week, double-blind, placebo-controlled trial will examine whether daily supplementation with the Lab4P probiotic can improve cognitive performance and metabolic health in overweight and obese adults aged 18 to 40. Seventy participants will be randomly assigned to receive either Lab4P or a placebo. The study will assess changes in memory, executive function, and processing speed, along with blood glucose control, cardiovascular function, cholesterol levels, body composition, and markers of inflammation. The study will also analyse changes in the gut microbiome and evaluate the safety and tolerability of the probiotic.