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Ramp / Heart Rhythm Disorders / Implantable Cardioverter Defibrillator (ICD) · Interventional Study
ClinicalTrials.gov · September 4, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a prospective, pragmatic cluster randomized trial registration comparing burst versus ramp anti-tachycardia pacing strategies in ICD patients. No results are currently available; the study is actively recruiting and will follow participants over approximately 10 years of device lifetime.
Interventional, Randomized, Parallel, Open label, Treatment purpose. Heart Disease, Implantable Cardioverter Defibrillator (ICD), Heart Rhythm Disorders, Ventricular Tachyarrhythmias; age from 18 Years. Intervention: Burst; Ramp. Compared with: Burst versus Ramp ATP programming after initial ATP in the VT zone (180–249 beats per minute). n = 3,980. 1 site: Denmark.
This is a prospective, pragmatic cluster randomized trial registration comparing burst versus ramp anti-tachycardia pacing strategies in ICD patients. No results are currently available; the study is actively recruiting and will follow participants over approximately 10 years of device lifetime.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
This is a registry record describing a planned pragmatic cluster-randomized trial with no results reported; enrollment is ongoing and outcome data collection extends over a 10-year follow-up period.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07354347). This is a study registration, not published results. Lead sponsor: Rigshospitalet, Denmark. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 3980 participants (ESTIMATED). Conditions: Heart Disease, Implantable Cardioverter Defibrillator (ICD), Heart Rhythm Disorders, Ventricular Tachyarrhythmias. Interventions: OTHER: Burst; OTHER: Ramp. Primary outcome measures: Arrhythmia cessation , The lifetime of the ICD, estimated 10 years. Brief summary: This is a pragmatic, two-group, cluster randomized trial designed to compare strategies for the Anti Tachycardia Pacing (ATP)-setting in the ventricular tachyarrhythmias (VT) zone when implanting a new implantable cardioverter defibrillator (ICD) in patients with heart disease in hospitals in Denmark. The strategies are: "Burst" or "Ramp" after 1. ATP (which is always burst) in VT zone. VT zone is defined between 180-249 (up to 269 in special cases) heartbeats per minute. The ICD will give either: Burst: The ICD is programmed to give ATP with 4 bursts. Or Ramp: The ICD is programmed to give ATP with 1 burst and 3 ramps. The participating hospitals will be assigned to one of two intervention strategies for periods of 4-months. The given intervention will follow the patient/ICD throughout the life time of the ICD, but with the possibility to reprogram at any time (intention to treat). It is calculated that the study needs a total of 398 events (second to fourth ATP), which is estimated to require 3980 implanted ICDs. The participants will be followed until the end of the ICD life, which is estimated to be around 10 years.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.