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Hemoglobinopathies and Related Disorders / Iron Metabolism and Disorders · Journal article
Scientific Reports · August 7, 2026
Reinforces what was already believed, rather than introducing something new.
This cross-sectional analysis of 4,050 Turkish adults reports an overall anemia prevalence of 13.6%, with marked sex disparity (19.3% women vs 4.8% men) and predominance of microcytic morphology (51.9%), consistent with iron deficiency as a major contributor. The findings establish baseline epidemiological burden and identify higher-risk subgroups (women, lower education, urban residence) but provide no mechanistic or intervention data.
Cross-sectional analysis of a prospective cohort baseline. Turkish adults aged 35–70 years enrolled in the PURE Türkiye cohort between 2008 and 2009; community-based recruitment across urban and rural areas in eight provinces; 4,050 participants with available hemoglobin measurements.. n = 4,050. Eight provinces in Türkiye (urban and rural areas).
Overall anemia prevalence 13.6% (4,050 participants aged 35–70 years) Sex disparity: 19.3% in women vs 4.8% in men (p < 0.001) Microcytic anemia most common subtype at 51.9%, followed by normocytic 48.1%
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Clinicians should recognize that anemia affects >1 in 7 Turkish adults, with substantially higher burden in women and those with lower education. The predominance of microcytic morphology suggests iron deficiency screening and supplementation strategies should target these high-risk groups.
Cross-sectional prevalence study in a nationally representative cohort quantifying anemia burden and morphological subtypes in Turkish adults; confirms expected patterns (higher in women, lower socioeconomic groups) but lacks intervention or comparative treatment data.
As stated by the source record.
Quoted from the source exactly as published.
Clinicians should recognize that anemia affects >1 in 7 Turkish adults, with substantially higher burden in women and those with lower education. The predominance of microcytic morphology suggests iron deficiency screening and supplementation strategies should target these high-risk groups.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Abstract To determine the prevalence, severity, and morphological subtypes of anemia among adults aged 35–70 years in Türkiye and to examine their distribution according to sex, age, educational level, and urban–rural residence. Cross-sectional analysis of baseline data from a nationally representative prospective cohort study. Community-based study conducted in urban and rural areas across eight provinces in Türkiye. A total of 4,050 adults aged 35–70 years enrolled in the Prospective Urban Rural Epidemiology (PURE) Türkiye cohort between 2008 and 2009 with available hemoglobin measurements. Anemia was defined and classified according to World Health Organization criteria. Primary outcomes were the prevalence and severity of anemia. Secondary outcomes included morphological subtypes based on mean corpuscular volume, mean corpuscular hemoglobin concentration, and red cell distribution width, as well as associations with sociodemographic characteristics and estimated dietary iron and vitamin B12 intake. Overall, 13.6% of participants had anemia, with a significantly higher prevalence in women than in men (19.3% vs. 4.8%; p < 0.001). Microcytic anemia was the most common subtype (51.9%), followed by normocytic anemia (48.1%). Among individuals with anemia, approximately 37% had hypochromic microcytic anemia with elevated red cell distribution width, suggestive of iron deficiency. Anemia prevalence showed an inverse association with educational level ( p = 0.009) and was slightly higher in urban than in rural areas (14.4% vs. 12.2%; p = 0.049). Estimated dietary iron and vitamin B12 intake did not differ significantly across anemia subtypes or hemoglobin categories, except for lower vitamin B12 intake among anemic men. Anemia affects a substantial proportion of adults aged 35–70 years in Türkiye, particularly women and individuals with lower educational attainment. The predominance of hypochromic microcytic anemia indicates that iron deficiency and non-nutritional factors may play an important role. These findings support the need for targeted public health strategies and routine anemia screening in high-risk adult populations.
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