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Life sciences · Review
International Journal of Community Medicine and Public Health · July 31, 2026
Early or partial results. Treat as a signal, not a conclusion.
This systematic review synthesizes epidemiological data from 14 observational studies on major limb amputation in India, involving 7,272 patients. Trauma accounts for the majority of amputations (73.1%), with males and lower-limb involvement predominating, but the review does not test interventions or compare treatment strategies, limiting its strength to descriptive epidemiology.
Systematic review of observational studies. Studies of patients with major limb amputation in India; specific eligibility criteria not detailed in abstract.. n = 7,272. India.
Trauma accounted for 5,316 cases (73.1%) of major limb amputations; non-traumatic causes for 1,956 cases (26.9%) Males represented 81.3% of reported patients Lower-limb amputations accounted for 90.8% of all reported amputations
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This review provides descriptive epidemiological context for major limb amputation burden in India but does not evaluate interventions or outcomes. Clinicians should use these data to understand disease prevalence and patterns rather than to guide individual patient management.
Systematic review of 14 observational studies describing epidemiological patterns in India; no intervention tested, no comparative analysis, and heterogeneity of included studies limits strength of synthesis.
As stated by the source record.
Quoted from the source exactly as published.
This review provides descriptive epidemiological context for major limb amputation burden in India but does not evaluate interventions or outcomes. Clinicians should use these data to understand disease prevalence and patterns rather than to guide individual patient management.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Major limb amputation remains an important cause of disability worldwide and is associated with substantial physical, psychological, social, and economic consequences. This study aimed to evaluate the epidemiology, etiology, and regional variation of major limb amputations in India. A systematic review was conducted in accordance with PRISMA guidelines. PubMed, Scopus, Web of Science, and Google Scholar were searched from January 1980 to March 2026. Of 150 records identified, 14 studies met inclusion criteria. A total of 7,272 patients were analyzed. Trauma accounted for 5,316 cases (73.1%) and non-traumatic causes for 1,956 cases (26.9%). Males represented 81.3% of reported patients and lower-limb amputations accounted for 90.8% of all reported amputations. Major limb amputation remains a significant public health challenge in India. Strengthening injury-prevention initiatives, improving management of diabetes and vascular disease, and expanding access to rehabilitation and prosthetic services may help reduce the burden of limb loss in India.
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