Time Restricted Eating / Spinal Cord Injury / Obesity · Interventional Study

Time Restricted Eating to Mitigate Obesity in Veterans With Spinal Cord Injury

ClinicalTrials.gov · August 19, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a registry record for an active feasibility study, not a results report. The study aims to test adherence to time-restricted eating in 15 veterans with spinal cord injury and obesity over 6 weeks, with no outcomes yet posted. The investigators explicitly state this work is intended to inform the design of a future randomized controlled trial.

What was studied

Interventional, Single Group, Open label, Other purpose. Spinal Cord Injury, Obesity; age from 18 Years; to 89 Years. Intervention: Time Restricted Eating. n = 15. 1 site: United States.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

This feasibility study does not yet provide clinical evidence; results are needed before any practice recommendations can be made. The planned future RCT may eventually inform obesity management strategies in this underserved population.

Plain-language summary

This is a feasibility study with no results reported, designed to test adherence to time-restricted eating in a small convenience sample of 15 veterans with spinal cord injury and obesity over 6 weeks.

Study design

As stated by the source record.

MethodsPrimary outcome measure: Change in the daily eating window (assessed at Measured weekly from baseline to week 6)

DesignInterventional, Single Group, Open label, Other purpose

PopulationSpinal Cord Injury, Obesity; age from 18 Years; to 89 Years

Sample size15

InterventionTime Restricted Eating

Setting1 site: United States

Reported figures

Quoted from the source exactly as published.

Sample size15

Primary outcome measureChange in the daily eating window, measured weekly from baseline to week 6

Study duration6 weeks

Clinical bottom line

Caveats

This is a registry record with no results posted; no efficacy or adherence data are available
Single-arm design with convenience sampling limits causal inference
Small sample (n=15) designed for feasibility assessment, not hypothesis testing
No comparator group or control condition

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

limited

Single-arm feasibility study; no control group or randomization

Directness

moderate

Tests behavioral intervention in target population with relevant conditions

Consistency

insufficient

Registry record only; no results reported for comparison

Risk of bias

limited

No blinding; convenience sampling; no comparator

Sample adequacy

limited

n=15 in convenience sample; designed as feasibility pilot only

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT05921487). This is a study registration, not published results. Lead sponsor: VA Office of Research and Development. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 15 participants (ACTUAL). Conditions: Spinal Cord Injury, Obesity. Interventions: BEHAVIORAL: Time Restricted Eating. Primary outcome measures: Change in the daily eating window , Measured weekly from baseline to week 6. Brief summary: Spinal cord injury (SCI) causes paralysis and muscle atrophy and leads to weight gain and obesity. Obesity directly contributes to functional impairment and cardiometabolic dysfunction. There is a critical need to reduce the growing prevalence of obesity and cardiometabolic disease after SCI. My overall objective in this project is to gather crucial feasibility data on time restricted eating (TRE), a novel form of intermittent fasting. TRE is a straightforward method to induce weight loss without the need for calorie counting. TRE allows individuals to eat all their daily calories in a time restricted window and fast outside that window. A growing body of literature supports the safety and efficacy of TRE. Given the feasibility, high adherence, and substantial benefits of TRE in able-bodied individuals, it is important to test TRE to determine its feasibility in Veterans with SCI. The investigators will first test this intervention in Veterans with paraplegia, who are at greatest risk of muscle-joint upper body injury given the need to support body weight during activity. The investigators will determine adherence to a TRE window for 6-weeks duration in a convenience sample of Veterans with paraplegia and obesity. Based on the expected outcomes of good adherence, this study will lay the groundwork for future work by informing the design of a randomized controlled trial to test the efficacy of TRE to facilitate weight loss and improve function.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

Time Restricted EatingSpinal Cord InjuryObesityNCT05921487VA Office of Research and Development