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Life sciences · Journal article
Journal of Cancer Education · August 18, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a descriptive implementation case study documenting the redesign and scaling of a tobacco cessation program at a single NCI cancer center using the RE-AIM framework. The program achieved a ten-fold increase in patient volume and reported a 31% 7-day point prevalence quit rate, but the study lacks a comparator, baseline quantification, or external replication to establish clinical efficacy or generalizability.
Single-center implementation case study using RE-AIM framework. Patients with cancer at an NCI-designated comprehensive cancer center. Intervention: Evidence-based tobacco cessation program with standardized EMR workflows, tobacco registry, certified tobacco specialists, and multidisciplinary collaboration. One NCI comprehensive cancer center (location not specified).
Ten-fold increase in patients seen for tobacco cessation services following program optimization 31% 7-day point prevalence of cessation achieved in the optimized program Successful implementation of standardized EMR workflows, tobacco registry, and addition of certified tobacco specialists
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
This case study demonstrates that systematic implementation of evidence-based tobacco cessation care using organizational and workflow redesign can substantially increase patient engagement and yield clinically meaningful quit rates. However, the lack of baseline data, control comparison, or multi-site validation limits the strength of inference about which implementation elements drive success or how results would generalize.
Implementation case study using RE-AIM framework at a single cancer center; demonstrates feasibility and process outcomes (ten-fold increase in patient volume, 31% cessation rate) but lacks a comparator arm, pre/post quantitative design, or external validation.
As stated by the source record.
Quoted from the source exactly as published.
This case study demonstrates that systematic implementation of evidence-based tobacco cessation care using organizational and workflow redesign can substantially increase patient engagement and yield clinically meaningful quit rates. However, the lack of baseline data, control comparison, or multi-site validation limits the strength of inference about which implementation elements drive success or how results would generalize.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Approximately 60% of patients with cancer have a history of smoking, and 20% continue to smoke after diagnosis. Despite the importance of smoking cessation for patients with cancer, it has been estimated that half of these patients are not offered smoking cessation treatment. Smoking cessation is an important element of comprehensive cancer care, and as such, the NCI developed the Cancer Center Cessation Initiative (C3I) with the goal of implementing sustainable tobacco cessation care. This paper addresses the design, implementation and sustainability of an evidence-based tobacco treatment program at an NCI comprehensive cancer center using the RE-AIM framework. The Reach, Effectiveness, Adoption, Implementation, and Maintenance goals were achieved through a multidisciplinary collaboration that led to the successful expansion of an evidence-based, yet under-resources and under-utilized tobacco cessation program into an organization-wide program employing standardized electronic medical records (EMR) workflows, a tobacco registry, additional certified tobacco specialists, and a strong programmatic and evaluation team including clinical and population science leadership. The program optimization led to a ten-fold increase in patients seen for tobacco cessation services and a 31% 7-day point prevalence of cessation. This paper serves to provide both a case study and guide on how to use RE-AIM to evaluate other cancer education programs and perhaps other areas of education, including vaping, nicotine replacement therapy, and relapse. This study highlights the importance of tobacco treatment as part of comprehensive cancer care and serves as a case-study for the usage of RE-AIM to design, implement, and evaluate health education programs.
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