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Life sciences · Observational Study
ClinicalTrials.gov · November 9, 2026
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Observational Study.
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Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
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Registry record from ClinicalTrials.gov (NCT07925346). This is a study registration, not published results. Lead sponsor: Bitlis Eren University. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 484 participants (ACTUAL). Conditions: Depression, Life Satisfaction. Primary outcome measures: Life Satisfaction Score , Baseline (single assessment at enrollment). Brief summary: This observational, cross-sectional study was designed to investigate the relationship between physical activity and mental health among university students, with particular emphasis on the potential mediating roles of perceived social support and self-esteem. The study included 484 university students (309 males and 175 females). Data were collected through an online survey using standardized self-report questionnaires assessing physical activity, perceived social support, self-esteem, depressive symptoms, and life satisfaction. The primary objective was to examine whether perceived social support and self-esteem functioned as individual and sequential mediators in the associations between physical activity and mental health outcomes. Life satisfaction and depressive symptoms were evaluated as separate outcome variables. Statistical analyses were conducted using IBM SPSS Statistics version 24 and the PROCESS macro version 4.0. Serial mediation analysis was employed to examine direct and indirect statistical associations between physical activity and the selected mental health indicators. As an observational study, no intervention was administered, and the cross-sectional design was intended to assess associations rather than establish causal relationships.