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Pulmonary Fibrosis / Cystic Fibrosis / Tuberous Sclerosis · Observational Study
ClinicalTrials.gov · September 10, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a registry entry for an ongoing observational study sponsored by NHLBI designed to evaluate the role of genetic factors in the development of multiple lung diseases including cystic fibrosis, pulmonary fibrosis, and sarcoidosis. No results are reported in this registry record; the study is currently recruiting and has not yet been completed or published.
Observational. Cystic Fibrosis, Pulmonary Fibrosis, Tuberous Sclerosis, Asthma, Pulmonary Sarcoidosis; age from 2 Years; to 90 Years; accepts healthy volunteers. Intervention: 1; 2. Compared with: In CT sub-study, low-dose CT imaging compared to standard CT imaging.. n = 3,500. 2 sites: United States.
This is a registry entry for an ongoing observational study sponsored by NHLBI designed to evaluate the role of genetic factors in the development of multiple lung diseases including cystic fibrosis, pulmonary fibrosis, and sarcoidosis. No results are reported in this registry record; the study is currently recruiting and has not yet been completed or published.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
This is an ongoing observational registry study with no results yet reported; it is designed to characterize genetic factors in lung disease across multiple conditions but carries no outcome data or effect estimates.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT00001532). This is a study registration, not published results. Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI). Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 3500 participants (ESTIMATED). Conditions: Cystic Fibrosis, Pulmonary Fibrosis, Tuberous Sclerosis, Asthma, Pulmonary Sarcoidosis. Primary outcome measures: evaluating the role of hereditary factor , 1 year. Brief summary: This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes directly involved in different diseases affecting the lungs of patients and healthy volunteers. Optional CT Sub-study The standard CT scan will be compared to the low dose radiation CT scan for the 150 subjects enrolled in the sub-study to assess the variation between the two techniques. Specifically, the quantitative computer aided detection of lung CT abnormalities from LAM can be compared to assess whether low radiation dose CT exams is an alternative to conventional CT to monitor disease status. This optional sub-study will be offered to up to 100 adult subjects with lung disease and up to 50 children age 9 and older with CF. Children will not be enrolled in the optional CT sub-study unless they have had a standard CT scan for medical purposes to use in comparison. One additional low dose radiation CT scan of the chest may be done as part of this sub-study when these subjects have their next annual CT scan.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.