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non-surgical periodontal therapy / Periodontal Disease / Obesity & Overweight · Interventional Study
ClinicalTrials.gov · August 18, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned interventional study comparing periodontal outcomes in people with obesity and periodontitis who are using GLP-1 receptor agonists versus those not on obesity medication, all receiving the same non-surgical periodontal therapy. No results are yet available, as recruitment has not begun. The study will measure changes in probing depth and inflammatory markers at 3 and 6 months.
Interventional, Non Randomized, Parallel, Single masking, Treatment purpose. Periodontal Disease, Obesity & Overweight. Intervention: Title: GLP-1 Receptor Agonist Group; Control Group. Compared with: Non-surgical periodontal therapy in participants not using any obesity medication. n = 40.
This is a planned interventional study comparing periodontal outcomes in people with obesity and periodontitis who are using GLP-1 receptor agonists versus those not on obesity medication, all receiving the same non-surgical periodontal therapy. No results are yet available, as recruitment has not begun. The study will measure changes in probing depth and inflammatory markers at 3 and 6 months.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Clinical trial registry record describing a planned interventional study with no results yet reported; enrollment not yet begun limits evidence strength.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07770906). This is a study registration, not published results. Lead sponsor: Cukurova University. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 40 participants (ESTIMATED). Conditions: Periodontal Disease, Obesity & Overweight. Interventions: PROCEDURE: non-surgical periodontal therapy. Primary outcome measures: Probing Depth , Baseline, 3 months- 6 months. Brief summary: This study aims to evaluate the effects of glucagon-like peptide-1 receptor agonist (GLP-1 RA) use on periodontal health and the response to non-surgical periodontal therapy in individuals with obesity and periodontitis. Participants with obesity and periodontitis will be divided into two groups: those who have been using a GLP-1 RA for at least 3 months and those who are not using any medication for obesity. All participants will receive the same non-surgical periodontal treatment, including oral hygiene instruction, scaling, and root planing. Periodontal clinical measurements and gingival crevicular fluid samples will be collected before treatment and at 3 and 6 months after treatment. The study will compare changes in periodontal health and inflammatory markers between the two groups to determine whether GLP-1 RA use is associated with periodontal health and the response to non-surgical periodontal therapy.
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