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Life sciences · Journal article
American Journal of Veterinary Research · July 31, 2026
A consensus or society position rather than new primary data.
This is a narrative review identifying critical knowledge gaps and research priorities for carbapenemase-producing Enterobacterales (CP-CRE) in companion animals. While CP-CRE infections remain rare in companion animals, outbreaks in veterinary hospitals are increasing and zoonotic transmission between people and animals has been documented, yet prevalence, carriage dynamics, risk factors, and evidence-based veterinary infection control practices remain poorly understood.
Narrative review. Companion animals and veterinary healthcare settings; epidemiologic literature on CP-CRE..
CP-CRE infections in companion animals remain relatively rare but outbreaks in veterinary hospitals are increasingly reported Case reports and epidemiologic studies support CP-CRE transmission between people and animals True prevalence of CP-CRE colonization in companion animals is unknown
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
A narrative review synthesizing epidemiology, identifying knowledge gaps, and outlining research priorities for CP-CRE in companion animals; provides expert perspective on prevention but lacks primary empirical data.
As stated by the source record.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no reported figures. That is a gap in the analysis, not a judgement about the study.
Carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) represent a growing threat to veterinary patients. Although CP-CRE infections in companion animals remain relatively rare, outbreaks in veterinary hospitals are increasingly being reported. Case reports and epidemiologic studies also support CP-CRE transmission between people and animals, making emergence in companion animals both an animal health and public health problem. However, substantial knowledge gaps limit understanding of the human and animal health impacts of CP-CRE in companion animals and of effective prevention and control interventions. For example, the true prevalence of CP-CRE colonization in companion animals is unknown, longitudinal dynamics of carriage remain poorly defined, and specific risk factors for acquisition in veterinary hospitals and community settings require further study. There are also unique structural and cultural challenges to implementing veterinary infection prevention and control practices, and evidence-based best practices tailored to veterinary settings are lacking. Diagnostic and surveillance infrastructure for companion animals is also highly fragmented, with inconsistent carbapenemase testing availability, limited mandatory reporting, and minimal capacity to rapidly detect and respond to outbreaks. This review synthesizes current clinical and molecular epidemiology of CP-CRE in companion animals; identifies critical gaps in diagnostics, surveillance, and veterinary infection prevention and control implementation; and outlines research priorities needed to mitigate and control CP-CRE within veterinary facilities. The companion Currents in One Health by Granick et al, JAVMA, 2026, addresses the clinical implications of the emergence of CP-CRE in companion animals and strategies for veterinary practitioners to mitigate spread.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.