Cancer Survivorship and Care · Journal article
Scientific Reports · September 10, 2026
Encouraging direction, but not yet definitive.
This quasi-experimental study compared VR-based patient education to conventional nurse-led education before radiation therapy in 84 first-time RT patients. Virtual reality produced a statistically significant but transient reduction in anticipatory anxiety immediately after CT simulation (p < 0.01), with the effect not sustained after treatment initiation; no benefits were demonstrated for knowledge acquisition or depressive symptoms.
Single-center quasi-experimental, non-randomized, two-group parallel study. Patients receiving radiation therapy for the first time at a regional hospital in Taiwan.. Intervention: Virtual reality-based patient education. Compared with: Conventional nurse-led education. n = 84. Regional hospital in Taiwan.
Knowledge scores improved in both groups; group-by-time interaction not significant (β = −1.67, 95% CI −11.04 to 7.71; p = 0.732) VR group showed greater anxiety reduction at first follow-up after CT simulation compared to conventional education (β = −1.61, 95% CI −2.62 to −0.62; p < 0.01) Anxiety benefit did not persist after treatment initiation (p = 0.742)
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VR patient education may provide short-term anxiolytic benefit before RT initiation but does not enhance knowledge or mood outcomes and the anxiety reduction is not maintained. Clinicians should not expect VR education to replace conventional education or produce durable psychological benefits in this setting.
A single-center quasi-experimental study with modest sample size showing a transient reduction in anticipatory anxiety with VR education, but no sustained benefit and no effect on knowledge or depressive symptoms.
As stated by the source record.
Quoted from the source exactly as published.
VR patient education may provide short-term anxiolytic benefit before RT initiation but does not enhance knowledge or mood outcomes and the anxiety reduction is not maintained. Clinicians should not expect VR education to replace conventional education or produce durable psychological benefits in this setting.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Radiation therapy (RT) is a critical aspect of cancer treatment; however, many patients experience anxiety before treatment due to unfamiliar procedures, equipment, and potential side effects. Effective patient education is important for strengthening patient understanding and psychological preparedness. This study evaluated the effectiveness of VR-based education compared with conventional nurse-led education in improving knowledge and psychological outcomes among patients undergoing first-time RT. A single-center quasi-experimental, non-randomized, two-group parallel study was conducted in a regional hospital in Taiwan. Patients receiving RT for the first time were assigned to either a VR education group or a conventional education group using a predetermined alternating allocation sequence. The final analysis included 43 patients in the VR group and 41 patients in the conventional education group. Knowledge was assessed at baseline and after computed tomography (CT) simulation, whereas psychological status was assessed at baseline, after CT simulation, and after the fifth RT session. Generalized estimating equations were used to examine group-by-time interaction effects. Knowledge scores improved in both groups, but the group-by-time interaction was not significant (β = −1.67, 95% CI − 11.04 to 7.71; p = 0.732). The VR group exhibited a greater reduction in anxiety at the first follow-up after CT simulation than the conventional education group (β = −1.61, 95% CI − 2.62 to − 0.62; p < 0.01); however, this effect was not sustained after treatment initiation ( p = 0.742). Depressive symptoms decreased over time in both groups, with no significant group-by-time interaction effects. Virtual reality education may have potential as an adjunct to conventional education for reducing short-term anticipatory anxiety before RT initiation, although it did not produce additional benefits for knowledge acquisition or depressive symptoms. Trial registration This study was retrospectively registered at ClinicalTrials.gov (NCT07598851) on May 11, 2026.
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