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Internet-Delivered Acceptance and Commitment Therapy / Intermittent Theta Burst Stimulation / Sleep Disturbance · Interventional Study
ClinicalTrials.gov · September 8, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a completed but unpublished randomized trial comparing internet-delivered Acceptance and Commitment Therapy, intermittent theta burst stimulation, their combination, and waitlist control for sleep quality in depressed adolescents. No efficacy or safety results are posted in this registry record; the study design appears sound, but clinical utility cannot be assessed until outcomes are reported.
Interventional, Randomized, Parallel, Double masking, Treatment purpose. Depressive Disorder, Sleep Disturbance; age from 11 Years; to 19 Years. Intervention: Combined iACT and iTBS; iACT Only; iTBS Only. Compared with: Waitlist Control — No Intervention. n = 160. 1 site: China.
This is a completed but unpublished randomized trial comparing internet-delivered Acceptance and Commitment Therapy, intermittent theta burst stimulation, their combination, and waitlist control for sleep quality in depressed adolescents. No efficacy or safety results are posted in this registry record; the study design appears sound, but clinical utility cannot be assessed until outcomes are reported.
No efficacy, safety, or adverse event results are reported in this registry record.
The source did not state who this applies to in practice.
This is a completed trial registry record with no posted results; the study design is sound but results remain unreported, making it an early-stage report that cannot yet inform clinical practice.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07807072). This is a study registration, not published results. Lead sponsor: Central China Normal University. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 160 participants (ACTUAL). Conditions: Depressive Disorder, Sleep Disturbance. Interventions: BEHAVIORAL: Internet-Delivered Acceptance and Commitment Therapy; DEVICE: Intermittent Theta Burst Stimulation. Primary outcome measures: Change in subjective sleep quality measured by the Pittsburgh Sleep Quality Index (PSQI) , Baseline to immediately postintervention (day 12) and baseline to 30-day follow-up (day 42). Brief summary: This study evaluated whether combining an internet-delivered Acceptance and Commitment Therapy program with intermittent theta burst stimulation improves subjective sleep quality in adolescents with depressive disorders and sleep disturbances. Acceptance and Commitment Therapy is a psychological treatment that teaches skills for accepting difficult thoughts and feelings, reducing unhelpful struggle with them, and taking actions consistent with personal values. Intermittent theta burst stimulation is a brief, noninvasive form of brain stimulation delivered over the left dorsolateral prefrontal cortex. A total of 152 adolescents aged 11 to 19 years were randomly assigned to one of four groups: combined internet-delivered Acceptance and Commitment Therapy plus intermittent theta burst stimulation, internet-delivered Acceptance and Commitment Therapy alone, intermittent theta burst stimulation alone, or a waitlist control group. Treatment was provided over 12 consecutive days. Participants completed assessments before treatment, immediately after treatment, and 30 days later. The study was registered retrospectively after participant recruitment and data collection had begun. The primary outcome was subjective sleep quality, measured with the Pittsburgh Sleep Quality Index. Secondary outcomes were depressive symptom severity and psychological flexibility. The study also assessed treatment exposure and adverse events, including headache or scalp discomfort associated with brain stimulation.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.