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Life sciences · Interventional Study
ClinicalTrials.gov · September 22, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT06537869). This is a study registration, not published results. Lead sponsor: Göteborg University. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 390 participants (ESTIMATED). Conditions: Depression Mild, Depression Moderate. Interventions: BEHAVIORAL: iCBT for depression. Primary outcome measures: MADRS-S (Montgomery and Asberg Depression Rating Scale) , Change from baseline scores MADRS-S scale at 3 months; MADRS-S (Montgomery and Asberg Depression Rating Scale) , Change from baseline scores MADRS-S scale at 6 months; MADRS-S (Montgomery and Asberg Depression Rating Scale) , Change from baseline scores MADRS-S scale at 12 months; MADRS-S (Montgomery and Asberg Depression Rating Scale) , Change from baseline scores MADRS-S scale at 24 months; MADRS-S (Montgomery and Asberg Depression Rating Scale) , Change from baseline scores MADRS-S scale at 36 months. Brief summary: This clinical trial aims to evaluate the potential benefits of internet cognitive behavioural therapy (iCBT) for elderly patients with mild/moderate depression and compare its effectiveness with the current treatment as usual (TAU) at primary care centres (PCCs). The specific aims are to study if: iCBT is as effective as TAU in reducing depressive symptoms iCBT is as effective as TAU in increasing quality of life iCBT is as effective as TAU in increasing the function in patients \>65 years and older with mild/moderate depression attending primary care, with the perspective of 36 months. Participants will: Work with the iCBT program (10-12 weeks) or become TAU at their PCCs. Followed-up at 3, 6, 12, 24 and 36 months of their symptoms, quality of life and function.