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Life sciences · Interventional Study
ClinicalTrials.gov · September 24, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT03220893). This is a study registration, not published results. Lead sponsor: Mayo Clinic. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 3023 participants (ACTUAL). Conditions: Breast Carcinoma. Interventions: PROCEDURE: Digital Breast Tomosynthesis (DBT); RADIATION: Scintimammography. Primary outcome measures: Rate of Detection of Invasive Cancers , At year 1 screening. Brief summary: This study compares molecular breast imaging (MBI) and digital breast tomosynthesis (DBT) in screening patients with dense breast tissue. Breast imaging may help doctors find breast cancer sooner, when it may be easier to treat. Molecular breast imaging (MBI) uses an injection of a small amount of radioactive material that is taken up in tissues of the body that are actively changing, such as breast cancer. A specialized camera, called a gamma camera, takes pictures of the gamma rays emitted by this material. MBI may detect cancers that are not visible on mammograms. This study may help researchers determine how MBI testing compares to DBT screening.