Life sciences · Preprint
arXiv · September 18, 2026
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A selective predictor acts as a safety gate: it returns an output only when the prediction appears sufficiently trustworthy. Deployments increasingly require this reliability to be certified at a target precision for every reporting unit of interest, such as a tool, policy label, or patient subgroup. The main difficulty is often not whether a granted certificate is valid, but whether finite calibration data can produce one at all. As the gate becomes safer or more fine-grained, some units may receive too little evidence to certify. We make this notion of availability computable through classical exact-binomial inversion and formulate reporting-partition selection, under a fixed group order, as a dynamic program that exposes the trade-off among safety, granularity, and served traffic. The resulting frontier reveals a large population opportunity that finite-sample estimation nearly erases: a truth-informed planner gains $0.157$ mean coverage over support balancing, whereas a naive estimator recovers only $0.005$, making recovery from finite data the central challenge. Constructing candidate partitions on one planning split and selecting among them on another recovers part of this gap, improving mean coverage over support balancing by $0.060$, with the direction reproduced in $59$ of $60$ model effects across three intent-routing datasets and two architectures. A complementary validity-preserving lever, reallocating the familywise error budget across reporting units, recovers additional coverage both with population quantities and noisy estimates. The same frontier recurs, with predictor-specific ceilings, across LLM tool-calling, content moderation, lesion classification, and recommendation. Certified availability is therefore a plannable deployment resource that determines when a safety gate can be certified, at what granularity, and over how much traffic.