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Life sciences · Interventional Study
ClinicalTrials.gov · October 13, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07485036). This is a study registration, not published results. Lead sponsor: University of Illinois at Chicago. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 30 participants (ESTIMATED). Conditions: Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy. Interventions: BEHAVIORAL: Contingency Management & Problem Solving Therapy; OTHER: Usual Care. Primary outcome measures: Change in postpartum depression symptoms , Screening, Baseline, 3 months; Alcohol use test results , Baseline, Weekly, 3 months; Change in alcohol use screening status , Screening, Baseline, 3 months; Change in alcohol-related negative consequences , Baseline, 3 months; Change in alcohol use , Baseline, 3 months; Change in reasons for drinking , Baseline, 3 months. Brief summary: This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms. The main questions it seeks to answer are: 1. How do new mothers fare with depressive symptoms and alcohol use in the first 12 months after giving birth? 2. Will a CM-PST intervention reduce depressive symptoms and alcohol use frequency among new mothers? 3. Is a CM-PST intervention practical for new mothers? The researchers will recruit approximately 30 new mothers and randomly select half to attend a 6-week CM-PST intervention. They will compare those who received the intervention versus those who did not to see if there are any differences in their depressive symptoms and alcohol usage. Participants will: * Complete 4 remote intervention sessions over 6 weeks * Conduct at-home urine drug tests 2x per week during the 6-week intervention * Answer online surveys about their mental health and alcohol use