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Life sciences · Preprint
arXiv · October 3, 2026
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Split Computing (SC) enables efficient deployment of Deep Neural Networks (DNNs) by partitioning inference between edge devices and cloud servers. However, intermediate feature representations are simultaneously exposed to hardware faults and adversarial attacks, which are traditionally evaluated independently. This paper presents a unified framework for the joint assessment of reliability and security in Split Computing. First, reliability is characterized through neuron-level fault injection using the Mean Relative Accuracy Degradation (MRAD) while security through feature-map-aware adversarial attacks simulations using the Attack Success Rate (ASR). Based on these complementary analyses, the Joint Vulnerability Score (JVS) is introduced, along with a confidence-aware extension that jointly captures prediction errors and confidence degradation. The framework is evaluated on ten Split Computing configurations based on ResNet-50 trained on ILSVRC-2012. Experimental results show substantial differences across compression strategies, with MRAD ranging from 44.3% to 61.2% under fault injection, while adversarial attacks achieve up to 98.8% ASR. Furthermore, the proposed joint metrics reveal vulnerability trends that remain hidden when reliability and security are analyzed independently, providing a more comprehensive methodology for designing dependable Split Computing systems.