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Life sciences · Interventional Study
ClinicalTrials.gov · November 4, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07915193). This is a study registration, not published results. Lead sponsor: Peking University Cancer Hospital & Institute. Recruitment status: ENROLLING_BY_INVITATION. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 150 participants (ESTIMATED). Conditions: Lung Neoplasms. Interventions: BEHAVIORAL: AI-guided personalized rehabilitation. Primary outcome measures: MDASI-LC quality-of-life scores , Before surgery; 1 week and 2 weeks after hospital discharge; and at the 1-month postoperative return visit; Forced Expiratory Volume in 1 Second (FEV1) , Before surgery, on the day of hospital discharge, and at the 1-month postoperative return visit; Forced Vital Capacity (FVC) , Before surgery; on the day of hospital discharge; and at the 1-month postoperative return visit.; Maximum Voluntary Ventilation (MVV) , Before surgery; on the day of hospital discharge; and at the 1-month postoperative return visit.. Brief summary: This study will evaluate whether a generative artificial intelligence (AI)-based rehabilitation support system can help older adults with lung cancer recover after lung surgery. Eligible participants aged 65 years or older who are scheduled for video-assisted thoracoscopic surgery (VATS) will be randomly assigned to receive either personalized perioperative rehabilitation guidance through the AI-based system or usual rehabilitation guidance. The system will provide guidance on exercise, nutrition, and psychological well-being before surgery and during recovery, and participants may report symptoms for follow-up guidance. The study will compare lung function and quality of life between the groups. It will also assess exercise tolerance, emergency department visits, hospital readmissions, and events related to use of the system.