Questionnaire / Lung Cancer · Observational Study

A Study of Lung Cancer Risk

ClinicalTrials.gov · August 14, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a recruiting observational study registered to identify factors associated with non-small-cell lung cancer risk in never-smokers over 3 years of follow-up. No results are posted in this registry record; the study is actively enrolling and remains preliminary.

What was studied

Observational. Lung Cancer; age from 40 Years; to 74 Years; accepts healthy volunteers. Intervention: Case patients; Control participants. n = 500. 7 sites: United States.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is a recruiting observational study with no results posted; it is a registry record describing planned enrollment and objectives, not completed research with outcomes.

Study design

As stated by the source record.

MethodsCase Control model. Prospective time perspective. Primary outcome measure: Identify factors associated with the risk of NSCLC (assessed at 3 years)

DesignObservational

PopulationLung Cancer; age from 40 Years; to 74 Years; accepts healthy volunteers

Sample size500

InterventionCase patients; Control participants

Setting7 sites: United States

Reported figures

Quoted from the source exactly as published.

Planned enrollment500

Primary outcome measureIdentify factors associated with the risk of NSCLC, 3 years

Study typeObservational

Caveats

No results are reported in this registry record; study is currently recruiting.
Study design, methods, and follow-up procedures not described in the registry summary.
No baseline characteristics, eligibility criteria, or analysis plan details provided.
Observational design without randomization or intervention; causality cannot be established.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

moderate

Observational design; no randomization, blinding, or intervention assignment.

Directness

moderate

Addresses lung cancer risk factors in never-smokers; outcome is clinically relevant.

Consistency

insufficient

Single study; no comparison to other work reported in registry record.

Risk of bias

insufficient

No information on blinding, confounding adjustment, or follow-up methods provided.

Sample adequacy

moderate

Planned enrollment of 500 participants; adequacy for risk factor analysis not justified.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT07701733). This is a study registration, not published results. Lead sponsor: Memorial Sloan Kettering Cancer Center. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 500 participants (ESTIMATED). Conditions: Lung Cancer. Interventions: OTHER: Questionnaire. Primary outcome measures: Identify factors associated with the risk of NSCLC , 3 years. Brief summary: The researchers are doing this study to learn more about factors that may increase the risk of lung cancer in people who have never smoked. This information may help predict which people who have never smoked may be more likely to get lung cancer.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

NCT07701733QuestionnaireMemorial Sloan Kettering Cancer CenterLung Cancer